Analysis and Simulations of Dynamic Models of Hepatitis B Virus
- Xisong Dong
- Cong Wang
- Gang Xiong
Abstract
A mathematical model consisting of two systems of Hepatitis B virus (HBV) infection is set up based on the model ofvirus dynamics and experimental observation of anti-viral drug therapy for HBV infection patients provided by Nowak. A
mathematical analysis of dynamic behaviors shows that the model has two kinds of equilibrium points, which represent the
patients’ complete recovery and HBV persistent infection at the end of the treatment with drug lamivudine, respectively.
Our model may provide possible quantitative interpretations for the long-time treatments of chronic HBV infections with
the drug lamivudine according to different model parameters, in particularly it may explain why the plasma virus of
Nowak et al’s patients turnover the original level after stopping the lamivudine treatment.
- Full Text:
PDF
- DOI:10.5539/jmr.v2n4p12
Journal Metrics
- h-index (December 2021): 22
- i10-index (December 2021): 78
- h5-index (December 2021): N/A
- h5-median (December 2021): N/A
( The data was calculated based on Google Scholar Citations. Click Here to Learn More. )
Index
- Academic Journals Database
- ACNP
- Aerospace Database
- BASE (Bielefeld Academic Search Engine)
- Civil Engineering Abstracts
- CNKI Scholar
- COPAC
- DTU Library
- EconPapers
- Elektronische Zeitschriftenbibliothek (EZB)
- EuroPub Database
- Google Scholar
- Harvard Library
- IDEAS
- Infotrieve
- JournalTOCs
- LOCKSS
- MathGuide
- MathSciNet
- MIAR
- PKP Open Archives Harvester
- Publons
- RePEc
- ResearchGate
- Scilit
- SHERPA/RoMEO
- SocioRePEc
- Standard Periodical Directory
- Technische Informationsbibliothek (TIB)
- The Keepers Registry
- UCR Library
- Universe Digital Library
- WorldCat
Contact
- Sophia WangEditorial Assistant
- jmr@ccsenet.org