Abstract

The dynamics of a system composed of hematopoietic stem cells and its relationship with neutrophils is ubiquitous due to periodic oscillating behavior induce cyclical neutropenia. Underlying the methodology of state feedback control with two time delays, double Hopf bifurcation occurs as varying time delay to reach its threshold value. By applying center manifold theory, the analytical analysis of system exposed the different dynamical feature in the classified regimes near double Hopf point. The novel dynamics as periodical solution and quasi-periodical attractor coexistence phenomena are explored and verified  by numerical simulation.

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