Abstract

ZnO substituted 45S5 bioactive - glasses and glass - ceramics were prepared. In vitro bioactivity of bioactive glasses and glass - ceramics, before and after exposed to simulated body fluid (SBF) solution for different time periods, were investigated by fourier transform infrared (FTIR) reflectance spectrometer with measuring the pH and the concentrations of silicon, sodium, calcium, phosphorus and zinc ions in SBF solution. The density, micro hardness and flexural strength of bioactive glasses and glass - ceramics were measured. Experimental results show that in vitro bioactivity nearly remains same by doping 1% of ZnO by weight, but after that as well as ZnO content increases in vitro bioactivity decreases. Crystallization of bioactive glasses decreases in vitro bioactivity. The density, micro hardness and flexural strength of bioactive glass - ceramics are higher than their respective bioactive glasses and these are also increasing with the increase of ZnO content.

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