Abstract

The present study was carried out to investigate the effect of polyzyme and lysoforte either alone or in combination on productive performance and some metabolic parameters in broiler chicks. Two hundred and forty, one day old, Cobb chicks were divided into four groups, the first group was fed on a basal ration without any additives and kept as a control, the second group was fed on a basal ration supplemented with polyzyme at a dose of 400 gm/ton ration, the third group was fed on a basal ration to which lysoforte was added at a dose of 250 gm/ton ration and the fourth group was fed on a basal diet to which polyzyme 400 g/ton and lysoforte 250 g/ton were added. Both feed additives either alone or in combination produced a significant improvement in body weight, body weight gain and feed conversion ratio during most of the first seven weeks. All supplemented groups showed no significant changes in the activities of ALP, AST, ALT and levels of creatinine and cholesterol versus control during the whole sampling periods. Polyzyme induced a significant increase in serum triglycerides level at the 4^th week of the experiment, while at the 6^th and 8^th week both polyzyme and lysoforte produced a significant increase in its level versus control. Blood glucose level was significantly increased in lysoforte supplemented groups at the 6^th weeks and in polyzyme and lysoforte supplemented groups at the 8^th weeks. No significant changes in TSH and T4 levels were recorded during the whole sampling periods. At the 8^th week the control group exhibited the lowest level of T3. The length of villi and depth of crypts of small intestine of supplemented groups were significantly higher than those of the control groups. All feed additives did not produce any obvious histopathological changes in the examined organs.

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