Phytochemical Screening and Antioxidant Activity of Origanum majorana Against Oxidative Stress Biomarkers
- Regis Augusto Norbert Deuschle
- Viviane Cecília Kessler Nunes Deuschle
- Gabriela Bonfanti-Azzolin
- Juliana Sorraila de Oliveira
- Queli Cristina Bitencourt Sostisso
- Jéssica dos Santos Goulart
- Mariana Spanamberg Mayer
- Roberta Cattaneo Horn
- Diego Pascoal Golle
Abstract
Origanum majorana is a cosmopolitan herb widely known as “marjoram”, which is used in traditional medicine and as family kitchen herb, for culinary purposes. Phytochemical screening was carried out and the antioxidant activity of Origanum majorana (Lamiaceae) hydroethanolic extract and infusion was investigated in this study. The hydroethanolic extract was screened through thin layer chromatography, subjected to spectrophotometry for polyphenols, flavonoids and tannins, as well as to 2,2-diphenyl-1-picrylhydrazyl free radical and iron reducing power assays. Fresh plant infusion was tested for the first time at three different concentrations against oxidative stress biomarkers in erythrocytes from HIV patients undergoing antiretroviral therapy. High antioxidant substance levels, as well as significant decrease in carbonylated protein, GSH and TBARS levels, were recorded, fact that showed the potential of O. majorana as exogenous antioxidant source. Our results indicated that O. majorana has good potential to prevent diseases caused by the overproduction of free radicals, and that it can be used as potential source of natural antioxidant agents.
- Full Text:
PDF
- DOI:10.5539/jas.v10n12p395
Journal Metrics
(The data was calculated based on Google Scholar Citations)
- Google-based Impact Factor (2018): 2.28
- h-index (December 2018): 31
- i10-index (December 2018): 304
- h5-index (December 2018): 22
- h5-median (December 2018): 27
Index
- ACNP
- AGRICOLA
- AGRIS
- BASE (Bielefeld Academic Search Engine)
- CAB Abstracts
- CiteFactor
- CNKI Scholar
- CrossRef
- DESY Publication Database
- DTU Findit (DTU Library)
- EBSCOhost
- Elektronische Zeitschriftenbibliothek (EZB)
- Excellence in Research for Australia (ERA)
- FindIt@Bham (UoB Library)
- Genamics JournalSeek
- Google Scholar
- HOLLIS (Harvard Library)
- Index Copernicus
- Infotrieve (Copyright Clearance Center)
- Jisc Library Hub Discover
- JournalTOCs
- Library of Congress
- LIVIVO (ZB MED)
- LOCKSS
- LSE Library
- Max Planck Institutes
- Mendeley
- MIAR
- Mir@bel
- Norwegian Centre for Research Data (NSD)
- OAJI
- Open J-Gate
- OskiCat (UCB Library)
- PKP Open Archives Harvester
- Publons
- Qualis/CAPES
- ROAD
- Scilit
- SHERPA/RoMEO
- Southwest-German Union Catalogue
- Standard Periodical Directory
- Stanford Libraries
- StarPlus (UoS Library)
- Technische Informationsbibliothek (TIB)
- Trove
- UCR Library
- Ulrich's
- UniCat
- Universe Digital Library
- University Library (USask)
- WorldCat
- WorldWideScience
- WRLC Catalog
- Zeitschriften daten bank (ZDB)
Contact
- Anne BrownEditorial Assistant
- jas@ccsenet.org