Variable Selection for Nonlinear Cox Regression Model via Deep Learning
- Kexuan Li
Abstract
Variable selection problem for the nonlinear Cox regression model is considered. In survival analysis, one main objective is to identify the covariates that are associated with the risk of experiencing the event of interest. The Cox proportional hazard model is being used extensively in survival analysis in studying the relationship between survival times and covariates, where the model assumes that the covariate has a log-linear effect on the hazard function. However, this linearity assumption may not be satisfied in practice. In order to extract a representative subset of features, various variable selection approaches have been proposed for survival data under the linear Cox model. However, there exists little literature on variable selection for the nonlinear Cox model. To break this gap, we extend the recently developed deep learning-based variable selection model LassoNet to survival data. Simulations are provided to demonstrate the validity and effectiveness of the proposed method. Finally, we apply the proposed methodology to analyze a real data set on diffuse large B-cell lymphoma.
- Full Text:
PDF
- DOI:10.5539/ijsp.v12n1p21
Journal Metrics
- h-index (December 2021): 20
- i10-index (December 2021): 51
- h5-index (December 2021): N/A
- h5-median(December 2021): N/A
( The data was calculated based on Google Scholar Citations. Click Here to Learn More. )
Index
- ACNP
- Aerospace Database
- BASE (Bielefeld Academic Search Engine)
- CNKI Scholar
- COPAC
- DTU Library
- Elektronische Zeitschriftenbibliothek (EZB)
- EuroPub Database
- Excellence in Research for Australia (ERA)
- Google Scholar
- Harvard Library
- Infotrieve
- JournalTOCs
- LOCKSS
- MIAR
- Mir@bel
- PKP Open Archives Harvester
- Publons
- ResearchGate
- SHERPA/RoMEO
- Standard Periodical Directory
- Technische Informationsbibliothek (TIB)
- UCR Library
- WorldCat
Contact
- Wendy SmithEditorial Assistant
- ijsp@ccsenet.org