Effect of Caffeine on Some Transferase Enzymes Activities


  •  Zyad J.Al-Qaisi    
  •  Selma Abdul Rudha Abbass    
  •  Amer Hasan Abdullah    

Abstract

This study was designed to show the effects of caffeine on the activities of aspartate aminotransferase (AST), alanine amino transferase (ALT), gama glutamate transferase (?-GT) enzymes in the sera. Caffeine demonstrated activation on (AST) and (ALT) activities, inhibitory effects on the (?-GT) activity, and these effects increased with increasing the concentration of the compound. Kinetic properties of (AST) and (ALT) activities revealed (by caffeine) non-competitive type of activation, and of (?-GT) activity competitive inhibitors



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