One-pot Preparation of beta–amino Carbonyl Compounds by Mannich Reaction Using MgO/ZrO2 as Effective and Reusable Catalyst

  •  Nagrik M.    
  •  Ambhore M.    
  •  Gawande B.    


A new one-pot and efficient three-component condensation of aldehyde, ketones, and amines in the presence of MgO/ZrO2 as an inexpensive and effective catalyst for the synthesis of beta-amino carbonyl compounds by Mannich reaction is described. The present methodology offers several advantages, such as good yields, Short reaction times and a recyclable catalyst with a very easy work up.

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  • ISSN(Print): 1916-9698
  • ISSN(Online): 1916-9701
  • Started: 2009
  • Frequency: semiannual

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