Synthesis, Characterization and Antimicrobial Study of Some New Cyclohexenone Derivatives


  •  Anil N. Mayekar    
  •  Hongqi Li    
  •  Hemmige Yathirajan    
  •  B. Narayana    
  •  N. Suchetha Kumari    

Abstract

A series of chalcones and its cyclohexenone derivatives derived from 6-methoxy-2-naphthaldehyde are described. The chalcones synthesized through Claisen-Schmidt condensation reaction were treated with ethylacetoacetate in presence of NaOH to get the cyclocondensed product ethyl-4-(aryl)-6-(6-methoxy-2-naphthyl)-2-oxo-cyclohex-3-ene-1-carboxylate. The synthesized compounds were characterized from elemental analysis and spectral data. Ethyl 4-(4-chlorophenyl)-6-(6-methoxy-2-naphthyl)-2-oxo-cyclohex-3-ene-1-carboxylate (4f) was studied by single crystal X-ray diffraction.



This work is licensed under a Creative Commons Attribution 4.0 License.