Abstract

Recently in this laboratory a novel series of Hector’s bases (1,2,4-thiadiazolidine) had been synthesized. 1-substituted-3formamidinothiocarbamides (1a-f) and 1,3-Bis(N-substitutedthioamido)guanidines (1g-l) were oxidatively cyclised by using liquid bromine as oxidizing agent in chloroform medium to synthesized yet new series of Hectors bases viz; 3-imino-5-substitutedimino-1,2,4-thiadiazolidine (2a-f) and 3-substitutedthioamidoimino-5-substitutedimino-1,2,4-thiadiazolidine (2g-l) respectively The oxidative cyclisation of (1a-l) was also carried out by making use of H₂O₂ in concentrated HCl as oxidizing agent. The Hector’s bases isolated in these reactions were characterized on the basis of conventional elemental analysis, chemical characteristics and IR and PMR spectral analysis.

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