Studies on the Preparation of (S)-3-chloro-phenyl-1-propanol by Catalytic Asymmetric Hydrogenation of B-chloro-propiophenone

  •  Yuxiang Wang    
  •  Mang Zheng    
  •  Xiaoyan Li    
  •  Langsong Si    
  •  Daofa He    
  •  Yajuan Zhao    


The supported iron-based chiral catalysts were applied in the asymmetric catalytic hydrogenation reaction of B-chloro-propiophenone, and effects of the asymmetric catalytic reduction reaction temperature, pressure and KOH concentration on the output and e.e.value were investigated respectively. Results indicated that the reaction output and e.e. value attained 99% and 90%, respectively, when temperature, pressure and concentration was 60 ?, 1.2 MPa and 2×10-2 mol/L, respectively.

This work is licensed under a Creative Commons Attribution 4.0 License.
  • ISSN(Print): 1916-9698
  • ISSN(Online): 1916-9701
  • Started: 2009
  • Frequency: semiannual

Journal Metrics

h-index (December 2022): 32

i10-index (December 2022): 145

h5-index (December 2022): N/A

h5-median(December 2022): N/A

( The data was calculated based on Google Scholar Citations. Click Here to Learn More. )