In-Vitro Antimicrobial Activity of Herbal Extracts From Tabuk Region (Kingdom of Saudi Arabia) Against Nosocomial Pathogens: A Preliminary Study

  •  Farheen Fatima    
  •  Showket Hussain Bhat    
  •  Mohammad Fahad Ullah    
  •  Faisel Abu-Duhier    
  •  Eram Husain    


AIM: The study aims to investigate the antimicrobial activity of herbal extracts from Tabuk region against nosocomial pathogens.

MATERIAL & METHODS: The plants included in this study were collected according to United States Department of Agriculture (USDA). The plants were grinded into fine powder using electric grinder, and the powder was transferred into air tight containers. Extracts of this powder was prepared in form of stock solution that was further used for preparing solutions of different concentrations. Antibacterial tests including minimum inhibitory concentration and maximum bactericidal concentration, broth dilution method, and well-diffusion method were performed.

RESULTS: The current study has determined the herbs that possess antimicrobial activity against the most common nosocomial pathogens. The sample extracts including Achinella fragrantissima, Artemisia judaica, Caralluma quadrangular, Cleome droserifera, Rhyza stricta, Moringa, and Ochradenus baccatus were tested for organisms including; Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Candida albicans. The results have depicted positive anti-microbial activity of herbal shrubs.

CONCLUSION: The results have demonstrated positive and promising anti-microbial activities against the nosocomial pathogens.

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