Abstract

To investigate the effects of extracts of Periplaneta Americana on anti-inflammation and decreasing pain, inhibitive effects of the extracts were investigated in different inflammatory models, for instance, cotton induced-granuloma tissue proliferous inflammation of mice, egg white induced rat paw edema, stress gastric ulcer of rats, acetic acid induced writhing response of mice, and hot metal board induced-pain of mice. Results showed that extracts of Periplaneta Americana played important roles in anti-inflammation induced by tumefaction, effusion and hyperplasia, and in decreasing pain. There was obviously statistical difference as compared with control group. It can be concluded that extracts of Periplaneta Americana are indeed worthy of further development for potential medicinal value.

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