Angiotensin-I Converting Enzyme Inhibitor Activity in Japanese Burdock Roots
- Shougo Kawamura
- Takayuki Murakami
- Kohji Ishihara
- Noriyoshi Masuoka
Japanese burdock roots were extracted with aqueous methanol solution. A compound having the inhibitory activity of angiotensin I-converting enzyme (ACE)[EC 188.8.131.52] was purified and identified as nicotianamine, (2S, 3’S, 3”S)-N-[N-(3-amino-3-carboxypropyl)-3-amino-3-carboxypropyl]azetidine-2-carboxylic acid. The compound content in burdock roots and related food products were determined. Data revealed that burdock root is a good source of nicotianamine (NA).
- Bella DongEditorial Assistant