Comparative Study on the Antifungal Activity of Some Di- and Tributyltin(IV) Carboxylate Compounds

Sutopo Hadi, Mita Rilyanti, Nurhasanah Nurhasanah

Abstract


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A series of di- and tributyltin(IV) carboxylate compounds prepared by reacting the dibutyltin(IV) dichloride and tributyltin(IV) chloride respectively via the organotin(IV) oxide with the respective carboxylic acids have been tested for antifungal activity against Fusarium oxysporum and Aspergillus niger in potatoes dextrose agar. The compounds synthesized were mainly characterized with IR and UV-Vis spectroscopies as well as based on the microanalytical data. The results showed that di- and tributyltin(IV) carboxylates prepared in general exhibit greater fungitoxicity than the organotin chlorides, the intermediate products and the free carboxylic acids. The organotin moiety plays an important role in deciding the antifungal activity of an organotin compound indeed true in our respect that the antifungal activity of tributyltin(IV) carboxylates  is more active than dibutyltin(IV) carboxylates .


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Modern Applied Science   ISSN 1913-1844 (Print)   ISSN 1913-1852 (Online)

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