International Journal of Chemistry
Synthesis of 3-substitutedmethylene-2H-thiopyrano[2,3-b] Pyridine-4(3H)-ones and Their Antifungal Activity In Vitro
Abstract
Six (Z)-3-substitutedmethylene-2H-thiopyrano[2,3-b]pyridin-4(3H)-ones were designed and synthesized. Their
structures were confirmed by MS and 1H-NMR and element analysis. Their antifungal activity was tested by micro
dilution broth susceptibility for eight kinds of fungi, and the results showed that the target compounds exhibited
activity against fungi tested to some extent. The compound 5a had the best antifungal effect among of the target
compounds.
structures were confirmed by MS and 1H-NMR and element analysis. Their antifungal activity was tested by micro
dilution broth susceptibility for eight kinds of fungi, and the results showed that the target compounds exhibited
activity against fungi tested to some extent. The compound 5a had the best antifungal effect among of the target
compounds.
This work is licensed under a Creative Commons Attribution 3.0 License.
International Journal of Chemistry ISSN 1916-9698 (Print) 1916-9701 (Online)
Copyright © Canadian Center of Science and Education
To make sure that you can receive messages from us, please add the 'ccsenet.org' domain to your e-mail 'safe list'. If you do not receive e-mail in your 'inbox', check your 'bulk mail' or 'junk mail' folders.