pH Metric Studies of Interaction of Synthesized Ligands 2-amino-4-hydroxy-6-methylpyrimidine and 1-(4-hydroxy-6-methylpyrimidino)-3-phenylthiocarbamide with Cu(II), Cd(II), Cr(II), Cations At 0.1 M Ionic Strength

Dipak T Tayade, Dinesh A Pund, Rahul Ashokrao Bhagwatkar, Dinesh B Rathod, Neha A Bhagwatkar

Abstract


Guanidine was successfully interacted with acetoacetic ester to synthesize 2-amino-4-hydroxy-6-methylpyrimidine
(L1) which on further treatment with phenylisothiocyanate furnishes
1-(4-hydroxy-6-methylpyrimidino)-3-phenylthiocarbamide (L2). The interactions of Cu(II), Cd(II), Cr(II) metal ions
with L1 and L2 have been studied at 0.1 M ionic strength in 70 % Dioxane-water mixture by Bjerrum method as
adopted by Calvin and Wilson, It is observed that Cu(II), Cd(II), Cr(II) metal ions form 1:1 and 1:2 complexes with
ligands (L1 and L2). The data obtained were used to estimate and compare the values of proton-ligand stability
constant (pK.) and metal-ligand stability constants (log k).The effect of substituents were studied from estimated
data (pK & log k).


Full Text: PDF DOI: 10.5539/ijc.v3n1p36

Creative Commons License
This work is licensed under a Creative Commons Attribution 3.0 License.

International Journal of Chemistry   ISSN 1916-9698 (Print)   ISSN 1916-9701 (Online)

Copyright © Canadian Center of Science and Education

To make sure that you can receive messages from us, please add the 'ccsenet.org' domain to your e-mail 'safe list'. If you do not receive e-mail in your 'inbox', check your 'bulk mail' or 'junk mail' folders.

----------------------------------------------------------------------------------------------------------------------------------------------------------------------

doaj_logo_new_120 proquest_logo_120images_120.