Synthesis, Characterization and Antimicrobial Study of Some New Cyclohexenone Derivatives

Anil N. Mayekar, Hongqi Li, Hemmige S Yathirajan, B. Narayana, N. Suchetha Kumari

Abstract


A series of chalcones and its cyclohexenone derivatives derived from 6-methoxy-2-naphthaldehyde are described. The chalcones synthesized through Claisen-Schmidt condensation reaction were treated with ethylacetoacetate in presence of NaOH to get the cyclocondensed product ethyl-4-(aryl)-6-(6-methoxy-2-naphthyl)-2-oxo-cyclohex-3-ene-1-carboxylate. The synthesized compounds were characterized from elemental analysis and spectral data. Ethyl 4-(4-chlorophenyl)-6-(6-methoxy-2-naphthyl)-2-oxo-cyclohex-3-ene-1-carboxylate (4f) was studied by single crystal X-ray diffraction.


Full Text: PDF DOI: 10.5539/ijc.v2n2p114

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International Journal of Chemistry   ISSN 1916-9698 (Print)   ISSN 1916-9701 (Online)

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