Studies in the Chemistry of Some New 1,2,4-thiadiazolidine by Oxidative Cyclisation

Dipak Tukaramji Tayade, Rahul Ashokrao Bhagwatkar, Radheshyam C. Panpalia


Recently in this laboratory a novel series of Hector’s bases (1,2,4-thiadiazolidine) had been synthesized. 1-substituted-3formamidinothiocarbamides (1a-f) and 1,3-Bis(N-substitutedthioamido)guanidines (1g-l) were oxidatively cyclised by using liquid bromine as oxidizing agent in chloroform medium to synthesized yet new series of Hectors bases viz; 3-imino-5-substitutedimino-1,2,4-thiadiazolidine (2a-f) and 3-substitutedthioamidoimino-5-substitutedimino-1,2,4-thiadiazolidine (2g-l) respectively The oxidative cyclisation of (1a-l) was also carried out by making use of H2O2 in concentrated HCl as oxidizing agent. The Hector’s bases isolated in these reactions were characterized on the basis of conventional elemental analysis, chemical characteristics and IR and PMR spectral analysis.

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International Journal of Chemistry   ISSN 1916-9698 (Print)   ISSN 1916-9701 (Online)

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