Oxidation of Some Sulfated Carbohydrates: Kinetics and Mechanism of Oxidation of Chondroitin-4-Sulfate by Alkaline Permanganate with Novel Synthesis of Coordination Biopolymer Precursor
- Ishaq Zaafarany
- Adil Gobouri
- Refat Hassan
Abstract
The kinetics of oxidation of chondroitin-4-sulfate as sulfated carbohydrates by alkaline permanganate has been investigated spectrophotometrically. The oxidation reaction was found to proceed through two-distinct stages. The first stage was found to be relatively fast involving the formation of unstable green [CS, MnVIO42-] and blue [CS, MnVO43-] biopolymeric coordination intermediates at wavelengths of 610 and 730 nm, respectively. The second stage was corresponding to a slow decomposition of such intermediates to give rise to keto-acid derivative and soluble-colloidal manganese (IV) as final oxidation products. The oxidation reaction was found to be base-catalyzed. The kinetic parameters have been evaluated and a tentative oxidation reaction mechanism in good consistent with the kinetic results was suggested and discussed. Novel keto-acid derivative has been synthesized. The reaction product was characterized and identified by elemental analysis and spectral data.- Full Text: PDF
- DOI:10.5539/jmsr.v2n4p23
This work is licensed under a Creative Commons Attribution 4.0 License.
Journal Metrics
The data was calculated based on Google Scholar Citations
Google-based Impact Factor (2021): 0.52
h-index (December 2021): 22
i10-index (December 2021): 74
h5-index (December 2021): N/A
h5-median (December 2021): N/A
Index
Contact
- John MartinEditorial Assistant
- jmsr@ccsenet.org