Angiotensin-I Converting Enzyme Inhibitor Activity in Japanese Burdock Roots

Shougo Kawamura, Takayuki Murakami, Kohji Ishihara, Noriyoshi Masuoka

Abstract


Japanese burdock roots were extracted with aqueous methanol solution. A compound having the inhibitory activity of angiotensin I-converting enzyme (ACE)[EC 3.4.15.1] was purified and identified as nicotianamine, (2S, 3’S, 3”S)-N-[N-(3-amino-3-carboxypropyl)-3-amino-3-carboxypropyl]azetidine-2-carboxylic acid. The compound content in burdock roots and related food products were determined. Data revealed that burdock root is a good source of nicotianamine (NA).


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DOI: http://dx.doi.org/10.5539/jfr.v4n2p51

Journal of Food Research   ISSN 1927-0887(Print)   ISSN 1927-0895(Online)

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